Coumarins and derivatives
Apexbio Technology LLC 3-Nitrocoumarin 28448-04-6 5mg
3-Nitrocoumarin (CAS 28448-04-6) is a selective inhibitor of phospholipase C- (PLC- ) an enzyme involved in cellular signal transduction through the hydrolysis of membrane phospholipids and subsequent generation of secondary messengers By suppressing PLC- catalytic activity 3-Nitrocoumarin disrupts related intracellular signaling pathways thereby enabling investigation of PLC- -mediated mechanisms in various physiological and pathological contexts This compound is widely utilized in studies focused on elucidating the roles of PLC- in disease models and fundamental biomedical research
eMolecules 6-Fluoro-4-hydroxycoumarin | 1G | Ships from Wood Dale, IL | Chem-Impex | 1994-13-4 | MFCD03094006 | MW: 180.13
Chem-Impex | 6-Fluoro-4-hydroxycoumarin | 1G | 1994-13-4 | MFCD07383035 | MW:177.22
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Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | 250 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye used for labeling proteins and nucleic acids.
- Amine-reactive succinimidyl ester of 7-hydroxycoumarin-3-carboxylic acid
- Blue fluorescent dye
- Used for labeling proteins
- Used for labeling nucleic acids
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 250 MG
4-Hydroxycoumarin is an orally active coumarin derivative, considered one of the most versatile heterocyclic scaffolds, frequently used in the synthesis of various organic compounds. It exhibits both electrophilic and nucleophilic properties. It functions as an HIV protease inhibitor and a tyrosine kinase inhibitor, and it also possesses anti-inflammatory, antibacterial, and anti-tumor effects.
- White to off-white solid
- Purity of 99.26% by HPLC
- Assay of 97.98%
- Loss on drying (LOD) of 1.2%
- Residue on ignition (ROI) of 0.09%
- Recommended storage at 4°C in sealed conditions, away from light and moisture
- Packaged in a brown glass bottle
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 1000 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in the synthesis of various organic compounds. It exhibits both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and also possesses anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile scaffold for organic synthesis
- Exhibits electrophilic and nucleophilic properties
- Acts as an HIV protease and tyrosine kinase inhibitor
- Possesses anti-inflammatory, antibacterial, and anti-tumor effects
- High purity white to off-white solid
- Shown to inhibit tumor growth in mouse melanoma models
- Reduces colitis symptoms in rat models
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 250mg
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | MFCD00037568 | ≥95.0% | 25 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye used for labeling proteins and nucleic acids.
- Amine-reactive succinimidyl ester
- Blue fluorescent dye
- Used for labeling proteins
- Used for labeling nucleic acids
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 100 G
4-Hydroxycoumarin is an orally active coumarin derivative, serving as a versatile heterocyclic scaffold for organic compound synthesis. It exhibits both electrophilic and nucleophilic properties. This compound acts as an HIV protease and tyrosine kinase inhibitor, demonstrating anti-inflammatory, antibacterial, and anti-tumor effects. It is primarily utilized as a laboratory chemical and in the manufacturing of various substances.
- Orally active coumarin derivative
- Versatile scaffold for organic synthesis
- Inhibits HIV protease and tyrosine kinase
- Exhibits anti-inflammatory, antibacterial, and anti-tumor effects
- Primarily used as a laboratory chemical
- Solid physical state, off-white appearance
- Chemically stable under normal conditions
Sigma Aldrich Fine Chemicals Biosciences 2-(Ethylamino)ethanol >=98% | 110-73-6 | MFCD00002841 | 500ML
2-(Ethylamino)ethanol >=98% | Purity: >=98% | Mol Wt: 89.14 | 110-73-6 | MFCD00002841 | 500ML
Medchemexpress LLC 7-Methoxycoumarin-3-carboxylic acid, SE | 150321-92-9 | 317.25 | 100 MG
7-Methoxycoumarin-3-carboxylic acid, SE can be used for the synthesis of hydrophilic dye compound 12. Compound 12 shows a homogeneous distribution inside the cell and represents a suitable probe for viscosity measurements in the cytoplasm. This product is for research purposes only and not for sale to patients.
- Used for the synthesis of hydrophilic dye compound 12
- Suitable probe for viscosity measurements in the cytoplasm
Apexbio Technology LLC Coumarin 91-64-5 50mg
Coumarin (91-64-5) is a small-molecule inhibitor targeting cytochrome P450 isoforms It is designed to modulate enzyme activity thereby regulating metabolic pathways Coumarin exerts its biological activity primarily through inhibition of cytochrome P450 enzymes In in vitro studies coumarin demonstrates enzyme inhibitory activity with an IC50 range of approximately 0 5 to 10 M depending on the isoform and experimental system Based on these pharmacological properties coumarin holds research potential in anticoagulant anti-inflammatory and anticancer agent discovery
Medchemexpress LLC Coumarin-d4 | 185056-83-1 | MFCD01861662 | 150.17 | 1 MG
Coumarin-d4 is the deuterium labeled Coumarin. Coumarin is the primary bioactive ingredient in Radix Glehniae, also known as Beishashen in China, which exhibits various pharmacological activities including anticancer, anti-inflammation, and antivirus properties.
- Deuterium labeled coumarin.
- Primary bioactive ingredient in Radix Glehniae.
- Possesses anticancer, anti-inflammation and antivirus activities.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Coumarin (standard) | 91-64-5 | 146.14 | 50 MG
Coumarin (Standard) is the analytical standard of Coumarin, intended for research and analytical applications. It is a potent and orally active anti-inflammatory agent, and also shows antinociceptive, antibacterial, antifungal, and anticancer activity. This product is for research use only and not sold to patients.
- The compound is a grade of analytical standard, serving as a reference standard for assays.
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Appearance: solid
- Color: white to off-white
- Structure classification: phenylpropanoids, coumarins
- Initial source: plants (Compositae Ambrosia psilostachya DC., Umbelliferae), microorganisms.