Coumarins and derivatives
TARGETMOL CHEMICALS INC Daphnetin 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50 7.67 uM), PKA (IC50 9.33 uM), and PKC (IC50 25.01 uM), also exhibit anti-oxidant and anti-inflammatory activities. Purity 99.82%
Chem-Impex International, Inc. Esculin hydrate | 531-75-9 | MFCD00149492 | 25G
Esculin hydrate, 531-75-9, MFCD00149492, 25G
Cayman Chemical 3azido7hydroxy Coumarin
A click-reactive fluorescent dye; Upon CuAAC in a biological system, a fluorescent product is produced that displays excitation/emission maxima of 404 and 477 nM, respectively; has been used for spatially restricted metabolite labeling and the detection of foodborne pathogens
Research Products International Corp Esculin, 500 G
- CAS Number: 531-75-9
- Molecular Formula: C15H16O9 • xH2O
- Molecualr Weight: 340.28 g/mol
AdipoGen Coumarin 102
Chemical. CAS 41267-76-9. Formula C16H17NO2. Molecular Weight 255.31. Coumarin 102 also known as coumarin 480, is a laser dye and is widely used as a dynamic fluorescent probe of both small molecules and host cavities, micelles, polymers and solids. Coumarin 102 belongs to 7-aminocoumarins with a structurally rigidized amino group. Spectral data lambdaex 390nm, lambdaem 466nm in ethanol, lambdalaser 480nm 461-513nm range.
AdipoGen Coumarin 102
Chemical. CAS 41267-76-9. Formula C16H17NO2. Molecular Weight 255.31. Coumarin 102 also known as coumarin 480, is a laser dye and is widely used as a dynamic fluorescent probe of both small molecules and host cavities, micelles, polymers and solids. Coumarin 102 belongs to 7-aminocoumarins with a structurally rigidized amino group. Spectral data lambdaex 390nm, lambdaem 466nm in ethanol, lambdalaser 480nm 461-513nm range.
Medchemexpress LLC Daphnetin (7,8-dihydroxycoumarin) | 486-35-1 | 99.8% | 178.14 | 5 MG
Daphnetin (7,8-dihydroxycoumarin) is a coumarin derivative found in plants of the Genus Daphne. It is a potent, orally active protein kinase inhibitor.
- Has IC50s of 7.67 μM, 9.33 μM, and 25.01 μM for EGFR, PKA, and PKC in vitro, respectively.
- Triggers ROS-induced cell apoptosis.
- Induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway.
- Possesses anti-inflammatory activity, inhibiting TNF-α, IL-1β, ROS, and MDA production.
- Exhibits schizontocidal activity against malaria parasites.
- Can be utilized in research for rheumatoid arthritis, cancer, and anti-malarial purposes.
Cayman Chemical 3azido7hydroxy Coumarin
A click-reactive fluorescent dye; Upon CuAAC in a biological system, a fluorescent product is produced that displays excitation/emission maxima of 404 and 477 nM, respectively; has been used for spatially restricted metabolite labeling and the detection of foodborne pathogens
Medchemexpress LLC Coumarin | 91-64-5 | MFCD00006850 | 146.15 | 1 G
Coumarin is a potent and orally active anti-inflammatory agent. It also shows an antinociceptive effect, and antibacterial, antifungal, and anticancer activity.
- Potent and orally active anti-inflammatory agent
- Shows antinociceptive effect
- Exhibits antibacterial, antifungal, and anticancer activity
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 |
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 |
Cayman Chemical CoumarIn BoronIc AcId 50mg
A fluorescent probe for direct detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide; reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s); COH displays ex/em = 332/470 nm, respectively
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 | 25G
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 25G
Cayman Chemical CoumarIn hydrazIn 25mg
An aromatic hydrazine-containing fluorophore that reacts with aldehydes or ketones for fluorescent labeling; acts as a sensor for oxidative stress by detection of carbonylated biomolecules in live cells; ex/em = 365/430-550 nm; produces a red shift in emission upon hydrozone formation; displays a large Stokes shift of approximately 195 nm
Cayman Chemical Coumarin Boronic Acid pinacol
A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively
